Assessment of adrenal cortex function in a group of HIV infected patients in sub-Saharan-Africa

The relationship between adrenal insufficiency and the HIV infection have been less investigated. aim of this study was to assess cortex function according stage in a group HIV-infected patients sub-Saharan Africa. We conducted cross-sectional 60 consenting subjects consisted 20 healthy controls 40 divided equally into 4 groups infection. Plasma cortisol levels were measured at baseline after synacthen stimulation by ELISA test. Basal post-synacthen comparable infected patients. Overall, majority had normal baseline. Only 5% absolute insufficiency. doubled their stimulation. They considered as having function. Adrenal seems be preserved However, late disease could an impairment therefore should placed on supplementation. Key words: function, cortisol, synacthen, patients, Africa.&nbsp